Theoretical study of Al(III)-catalyzed conversion of glyoxal to glycolic acid: dual activated 1,2-hydride shift mechanism by protonated Al(OH)3 species.

نویسندگان

  • Takashi Ohshima
  • Yoshihiro Yamamoto
  • Usaji Takaki
  • Yoshihisa Inoue
  • Takuya Saeki
  • Kenji Itou
  • Yusuke Maegawa
  • Takanori Iwasaki
  • Kazushi Mashima
چکیده

Density functional theory calculations demonstrate that Al(III)-catalyzed conversion of glyoxal to glycolic acid proceeds via a 7-membered dual Lewis acid-hydrogen bonding activation transition state of the 1,2-hydride shift, rather than the previously proposed 5-membered metal-alkoxide chelate activation transition state.

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عنوان ژورنال:
  • Chemical communications

دوره 19  شماره 

صفحات  -

تاریخ انتشار 2009